A portfolio of work across tuberculosis and malnutrition, pathogen genomics, antimicrobial resistance, One Health, bioprospecting, microbial biotechnology and computational molecular discovery.
Genomics, omics and translational discovery.
These projects connect molecular evidence with infectious disease biology, antimicrobial resistance, One Health transmission, African biological resources and computational approaches for discovery-oriented biomedical science.
Postdoctoral work examining tuberculosis and malnutrition within a Kibongoto Infectious Disease Hospital–University of Virginia NIH-funded programme. The research direction links infection, nutrition, metabolic health and omics-based discovery.
Comparative genomic and phylogenomic studies of clinically important bacterial pathogens, including Klebsiella, Escherichia coli, Citrobacter, Pseudomonas and Staphylococcus aureus, with emphasis on antimicrobial resistance, virulence, sequence types, mobilomes and genomic epidemiology.
Development of One Health genomic approaches linking clinical, animal and environmental reservoirs to understand antimicrobial resistance movement, strain diversity and transmission ecology in Tanzania and the wider East African context.
Omics-guided exploration of African microbiomes and thermophilic systems for enzymes, DNA polymerase and DNA-binding protein isoforms, antimicrobial leads and biotechnology-relevant molecular resources.
Use of molecular docking, pathway-level target prioritisation, comparative conservation and integrative computational biology to identify potential anti-infective molecules and generate mechanistic hypotheses.