REUBEN S. MAGHEMBE
Pathogen genomics · Antimicrobial resistance Bioinformatics · Translational omics
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PUBLICATIONS

Selected Publications

Selected scholarly works across pathogen genomics, antimicrobial resistance, microbiome mining, bioprospecting, molecular docking, microbial biotechnology, infectious disease biology and mathematical modelling.

PUBLICATION PROFILE

Publications listed here represent selected scholarly works. A full and continuously updated publication record is available through Google Scholar and ORCID.

SELECTED WORK · 2025 · Research Article

Pangenome analysis of Tanzanian clinical Klebsiella pneumoniae reveals pandemic clones with high genome plasticity and versatile mobilome, virulome, and resistome profiles

Bahati Samweli Y., Maghembe Reuben S.

Microbiology Spectrum 0:e01947-25

Klebsiella pneumoniae Pangenome AMR Mobilome Virulome Resistome
SELECTED WORK · 2025 · Research Article

Regional genomic and phylogenomic insights into multidrug and colistin-resistant Klebsiella pneumoniae strains from Tanzania, Kenya, Uganda and Ethiopia

Bahati SY, Moto E, Makaranga A, Massawe JI, Maghembe RS

Current Microbiology 82:577

Klebsiella pneumoniae Phylogenomics Colistin resistance East Africa AMR
SELECTED WORK · 2020 · Review Article

Omics for bioprospecting and drug discovery from bacteria and microalgae

Maghembe R, Damian D, Makaranga A, Nyandoro SS, Lyantagaye SL, Kusari S, Hatti-Kaul R

Antibiotics 9

Omics Bioprospecting Drug discovery Bacteria Microalgae
SELECTED WORK · 2025 · Research Article

Genomic insight into the high-risk hypervirulent multidrug-resistant enteroaggregative-hemorrhagic Escherichia coli ST648/*a194 (serotype O8:H4) isolated from a 3-year-old patient with bloodstream infection in Uganda, sub-Saharan Africa

Maghembe RS, Magulye MAK, Makaranga A, Bahati S, Katagirya E, Wabwire-Mangen F

Gene Reports 39:102198

Escherichia coli ST648 Bloodstream infection Uganda Genomics AMR
SELECTED WORK · 2025 · Research Article

Potential of omics workflows for harnessing molecular-grade DNA polymerase and DNA-binding protein isoforms from African thermophilic microbiomes

Maghembe RS, Makaranga A, Ndunguru J, Bahati SY, Mark D, Kidulile C

Scientific African 29:e02854

Omics workflows Thermophilic microbiomes DNA polymerase DNA-binding proteins
SELECTED WORK · 2024 · Research Article

A sophisticated virulence repertoire and colistin resistance of Citrobacter freundii ST150 from a patient with sepsis admitted to ICU in a tertiary care hospital in Uganda, East Africa: insight from genomic and molecular docking analyses

Maghembe RS, Magulye MAK, Eilu E, Sekyanzi S, Makaranga A, Mwesigwa S, Katagirya E

Infection, Genetics and Evolution 105591

Citrobacter freundii ST150 Sepsis Colistin resistance Molecular docking
SELECTED WORK · 2024 · Research Article

Comprehensive genomics reveals novel sequence types of multidrug-resistant Klebsiella oxytoca with uncharacterized capsular polysaccharide K- and lipopolysaccharide O-antigen loci from the National Hospital of Uganda

Maghembe RS, Magulye MAK, Makaranga A, Moto E, Sekyanzi S, Mwesigwa S, Katagirya E

Infection, Genetics and Evolution 123:105640

Klebsiella oxytoca Multidrug resistance Capsular loci O-antigen Genomics
SELECTED WORK · 2024 · Book Chapter

Chapter 13 - Biosynthesis of endocannabinoids and phytocannabinoids

Maghembe RS, Makaranga A, Nyandoro SS

In Cannabis and Khat in Drug Discovery. Elsevier Science, pp. 277-297

Endocannabinoids Phytocannabinoids Biosynthesis Drug discovery
SELECTED WORK · 2024 · Research Article

Metagenome mining divulges virulent and multidrug-resistant Pseudomonas aeruginosa ST242 and Klebsiella michiganensis ST*1b23 coinfecting an 8-month-old meningitis infant under ICU in Kampala, Uganda, East Africa

Maghembe RS, Magulye MAK, Makaranga A, Nsubuga G, Sekyanzi S, Moto EA, Mwesigwa S, Katagirya E

Heliyon 10

Metagenome mining Pseudomonas aeruginosa Klebsiella michiganensis Meningitis AMR
SELECTED WORK · 2023 · Data Article

Complete genome sequence data of Priestia megaterium strain MARUCO02 isolated from marine mangrove-inhabited sediments of the Indian Ocean in the Bagamoyo Coast

Maghembe RS, Mdoe FP, Makaranga A, Mpemba JA, Mark D, Mlay C, Moto EA, Mtewa AG

Data in Brief 48:109119

Priestia megaterium Genome sequence Marine mangrove Bagamoyo
SELECTED WORK · 2021 · Research Article

Ligand-protein interactions of plant-isolated (9Z,12Z)-octadeca-9,12-dienoic acid with beta-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing

Mtewa AG, Bvunzawabaya JT, Ngwira KJ, Lampiao F, Maghembe R, Okella H, Weisheit A, Tolo CU, Ogwang PE, Sesaazi DC

Scientific African 12:e00824

KasA Anti-tubercular design Ligand-protein interaction Molecular docking
SELECTED WORK · 2021 · Research Article

Metabolic potential of the moderate halophile Yangia sp. ND199 for co-production of polyhydroxyalkanoates and exopolysaccharides

Romero Soto L, Thabet H, Maghembe R, Gameiro D, Van-Thuoc D, Dishisha T, Hatti-Kaul R

MicrobiologyOpen 10:e1160

Yangia Halophile Polyhydroxyalkanoates Exopolysaccharides
SELECTED WORK · 2024 · Research Article

Impact of drug dispersion on tumor-effector dynamics during combined chemo-immunotherapy with sensitivity analysis

Mashiku LR, Ndenda JP, Maghembe R, Shaw S

Applied Mathematical Modelling 134:148-174

Mathematical modelling Chemo-immunotherapy Tumor-effector dynamics
SELECTED WORK · 2025 · Data Article

Whole genome sequence of a virulent and multidrug-resistant Staphylococcus aureus strain MD02 isolated from a diabetic foot ulcer in Uganda

Makeri D, Eilu E, Odoki M, Adebayo IA, Maghembe R, Abubakar M, Muhwezi R, Pius T, Dilli PP, Akinola SA, Agwu E

BMC Genomic Data 26:50

Staphylococcus aureus Diabetic foot ulcer Whole genome sequence Uganda AMR
SELECTED WORK · 2024 · Research Article

Assessing the effect of sample storage time on viral detection using a rapid and cost-effective CTAB-based extraction method

Mark D, Tairo F, Ndunguru J, Kweka E, Saggaf M, Bachwenkizi H, Chiunga E, Lusana JL, Sikazwe G, Maghembe R

Plant Methods 20:64

CTAB extraction Viral detection Sample storage Plant Methods